kearny
September 20th, 2005
TranS1® Announces Series C Round of Financing

TranS1 has created a unique approach to the lumbar spine utilizing interventional radiology techniques. The product allows for minimally invasive fusion of the anterior interbody spine in the L5-S1 space – a procedure that previously could only be performed with open surgery. We believe that TranS1 can dominate the $800 million market associated with these fusions. Below, the company report raising capital to drive continued commercialization of their FDA-approved device.

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TranS1®, Inc., a development stage company focused on novel percutaneous products and procedures to treat lower back pain, today announced that it has completed a $25.7 million Series C round of financing. Thomas Weisel Healthcare Ventures led the round, with Advanced Technology Ventures (ATV), Delphi Ventures, Cutlass Capital and Sapient Capital also participating. Proceeds from the financing will be used for commercialization of Axial Lumbar Interbody Fusion (AxiaLIF™) System and completing development and initiation of clinical studies of the company's Percutaneous Nucleus Replacement (PNR™) for early stage degenerative disc disease. Forty to sixty percent of adults suffer from chronic back pain in the U.S. every year, and more than one million spine surgery procedures are performed annually in this country. Medical costs to treat back pain approach $24 billion per year.

TranS1® has developed a unique trans-sacral approach to accessing the lumbar spine through a percutaneous 1” incision. This unique, least invasive access enables surgeons to perform a range of spine fusion, nucleus and disc replacement procedures with specialized access instrumentation - avoiding the dissection or penetration of any surrounding spinal tissue. This spares the spine from further trauma and reduces recovery time and discomfort for patients.

“We are very enthusiastic about TranS1’s percutaneous approach to the spine. It is the only spinal access technology platform that enables definitive therapy in a truly minimally invasive manner, reducing operating room time and minimizing patient recovery time", said James Shapiro, General Partner at Thomas Weisel Healthcare Ventures and Kearny Venture Partners. "We are also very excited about working with Rick Randall again. The management team that Rick and the Founders have assembled is outstanding, making this a terrific opportunity for TWHVP."

TranS1 CEO Rick Randall said, "Leading investors like Thomas Weisel, ATV, Cutlass Capital, Delphi Ventures and Sapient Capital, are validating our early clinical adoption of AxiaLIF and vision of percutaneous solutions for a major leap forward in the lumbar spine surgery market. Low back pain affects millions of individuals each year, and our ability to make percutaneous spine fusion and disc replacement capabilities available, without the need to impact sensitive muscle, nerve and spinal support structures in any way, are major milestones in the care of those who suffer from serious spine disease."

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